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3. Acknowledgments. These studies were conducted under Contract No. HSM-42-71-95 between the Center for Studies of Narcotic and Drug Abuse of the Division of Narcotic Addiction and Drugo Abuse, NIMH, and the Research Triangle Institute. In addition, this investigation was supported by Public Health Service Research Grant No. RR-46 from the General Clinical Research Centers Branch of the Division of Research Resources. We thank Drs.Monique Braude andS. Szara, Center for Studies of Narcotic and Drug Abuse, NIMH, for their interest and encouragement of this program. We also thankCarolyn Bishop andDaynise Skeen for their technical assistance.