Simultaneous Detection of Precore/Basal Core Promoter Mutations in Hepatitis B Virus Using Arrayed Primer Extension

Author:

Ha Wai-Yan,Lau Chi-Chiu,Yue Patrick Y. K.,Hung Kaman K. M.,Chan Kelvin,Chui Siu-Hon,Chui Albert K. K.,Yam Wing-Cheong,Wong Ricky N. S.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology,Genetics,Molecular Medicine,General Medicine

Reference19 articles.

1. World Health Organization. Hepatitis B, fact sheet no. 204 [online]. Available from URL: http://www.who.int/mediacentre/factsheets/fs204/en/ [Accessed 2005 Jun 14]

2. Schlicht HJ, Von Brunn A, Theilmann L. Antibodies in anti-HBe positive sera bind an HBe protein expressed on the cell surface of human hepatoma cells: implications for virus clearance. Hepatology 1991; 13: 57–61

3. Chu CM, Yeh CT, Lee CS, et al. Precore stop mutant in HbeAg-positive patients with chronic hepatitis B: clinical characteristics and correlation with the course of HbeAg-toAnti-Hbe seroconversion. J Clin Microbiol 2002; 40: 16–21

4. Lai CL, Ratziu V, Yuen MF, et al. Viral hepatitis B. Lancet 2003; 362: 2089–94

5. Shumaker JM, Tollet JJ, Filbin KJ, et al. APEX disease gene resequencing: mutations in exon 7 of the p53 tumor suppressor gene. Bioorg Med Chem 2001; 9: 2296–78

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