Mesenchymal Stem Cells Ameliorate Cuprizone-Induced Demyelination by Targeting Oxidative Stress and Mitochondrial Dysfunction

Author:

Shiri Elham,Pasbakhsh Parichehr,Borhani‑Haghighi Maryam,Alizadeh Zohreh,Nekoonam Saied,Mojaverrostami Sina,Pirhajati Mahabadi Vahid,Mehdi Ali,Zibara KazemORCID,Kashani Iraj Ragerdi

Funder

Tehran University of Medical Sciences and Health Services

Université Libanaise

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Cellular and Molecular Neuroscience,General Medicine

Reference62 articles.

1. Abrams MB, Dominguez C, Pernold K, Reger R, Wiesenfeld-Hallin Z, Olson L, Prockop D (2009) Multipotent mesenchymal stromal cells attenuate chronic inflammation and injury-induced sensitivity to mechanical stimuli in experimental spinal cord injury. Restor Neurol Neurosci 27:307–321

2. Ayatollahi M, Hesami Z, Jamshidzadeh A, Gramizadeh B (2014) Antioxidant effects of bone marrow mesenchymal stem cell against carbon tetrachloride-induced oxidative damage in rat livers. Int J Organ Transplant Med 5:166

3. Barati S, Kashani IR, Tahmasebi F, Mehrabi S, Joghataei MT (2019) Effect of mesenchymal stem cells on glial cells population in cuprizone induced demyelination model. Neuropeptides 75:75–84

4. Brooks C, Cho S-G, Wang C-Y, Yang T, Dong Z (2010) Fragmented mitochondria are sensitized to bax insertion and activation during apoptosis. Am J Physiol Cell Physiol 300:C447–C455

5. Castro-Manrreza ME, Montesinos JJ (2015) Immunoregulation by mesenchymal stem cells: biological aspects and clinical applications. J Immunol Res. https://doi.org/10.1155/2015/394917

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