Computational Investigation on Electrostatic Loop Mutants Instigating Destabilization and Aggregation on Human SOD1 Protein Causing Amyotrophic Lateral Sclerosis
Author:
Publisher
Springer Science and Business Media LLC
Subject
Organic Chemistry,Biochemistry,Bioengineering,Analytical Chemistry
Link
http://link.springer.com/article/10.1007/s10930-018-09809-0/fulltext.html
Reference55 articles.
1. Kumar S, Nussinov R (2002) Close-range electrostatic interactions in proteins. ChemBioChem 3:604–617. https://doi.org/10.1002/1439-7633(20020703)3:7%3C604::AID-CBIC604%3E3.0.CO;2-X.
2. Zhou H-X, Pang X (2018) Electrostatic interactions in protein structure, folding, binding, and condensation. Chem Rev 118:1691–1741. https://doi.org/10.1021/acs.chemrev.7b00305
3. Nakamura H (1996) Roles of electrostatic interaction in proteins. Q Rev Biophys 29:1–90. https://doi.org/10.1017/S0033583500005746
4. Tan W, Pasinelli P, Trotti D (2014) Role of mitochondria in mutant SOD1 linked amyotrophic lateral sclerosis. Biochim Biophys Acta 1842:1295–1301. https://doi.org/10.1016/j.bbadis.2014.02.009
5. Karch CM, Borchelt DR (2008) A limited role for disulfide cross-linking in the aggregation of mutant SOD1 linked to familial amyotrophic lateral sclerosis. J Biol Chem 283:13528–13537. https://doi.org/10.1074/jbc.M800564200
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