Can We Pharmacologically Target Dishevelled: The Key Signal Transducer in the Wnt Pathways?
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Publisher
Springer International Publishing
Link
https://link.springer.com/content/pdf/10.1007/164_2021_527
Reference118 articles.
1. Angers S, Thorpe CJ, Biechele TL, Goldenberg SJ, Zheng N, MacCoss MJ, Moon RT (2006) The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-β-catenin pathway by targeting Dishevelled for degradation. Nat Cell Biol 8:348–357. https://doi.org/10.1038/ncb1381
2. Arend RC, Londoño-Joshi AI, Straughn JM, Buchsbaum DJ (2013) The Wnt/β-catenin pathway in ovarian cancer: a review. Gynecol Oncol 131:772–779. https://doi.org/10.1016/j.ygyno.2013.09.034
3. Badura L, Swanson T, Adamowicz W, Adams J, Cianfrogna J, Fisher K, Holland J, Kleiman R, Nelson F, Reynolds L, St. Germain K, Schaeffer E, Tate B, Sprouse J (2007) An inhibitor of casein kinase Iϵ induces phase delays in circadian rhythms under free-running and entrained conditions. J Pharmacol Exp Ther 322:730–738. https://doi.org/10.1124/jpet.107.122846
4. Bernatík O, Paclíkova P, Sri Ganji R, Bryja V (2020) Activity of Smurf2 ubiquitin ligase is regulated by the Wnt pathway protein Dishevelled. Cell 9:1147. https://doi.org/10.3390/cells9051147
5. Bibian M, Rahaim RJ, Choi JY, Noguchi Y, Schürer S, Chen W, Nakanishi S, Licht K, Rosenberg LH, Li L, Feng Y, Cameron MD, Duckett DR, Cleveland JL, Roush WR (2013) Development of highly selective casein kinase 1δ/1ε (CK1δ/ε) inhibitors with potent antiproliferative properties. Bioorg Med Chem Lett 23:4374–4380. https://doi.org/10.1016/j.bmcl.2013.05.075
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2. Frizzleds act as dynamic pharmacological entities;Trends in Pharmacological Sciences;2024-05
3. Pathway selectivity in Frizzleds is achieved by conserved micro-switches defining pathway-determining, active conformations;Nature Communications;2023-07-29
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