Overexpressed TTC3 Protein Tends to be Cleaved into Fragments and Form Aggregates in the Nucleus-Reference-Cited by-同舟云学术

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Overexpressed TTC3 Protein Tends to be Cleaved into Fragments and Form Aggregates in the Nucleus

Published:2018-09-10 Issue:1 Volume:21 Page:85-96
ISSN:1535-1084
Container-title:NeuroMolecular Medicine
language:en
Short-container-title:Neuromol Med

Author:

Gong Yueqing,Wang Kun,Xiao Sheng-Ping,Mi Panying,Li Wanjie,Shang Yu,Dou Fei

Funder

National Natural Science Foundation of China

Open Research Fund of the State Key Laboratory of Cognitive Neuroscience and Learning

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Neurology,Molecular Medicine

Link

http://link.springer.com/article/10.1007/s12017-018-8509-7/fulltext.html

Reference28 articles.

1. Antonarakis, S. E., Lyle, R., Dermitzakis, E. T., Reymond, A., & Deutsch, S. (2004). Chromosome 21 and Down syndrome: From genomics to pathophysiology. Nature Reviews Genetics, 5(10), 725–738.

2. Berto, G., Camera, P., Fusco, C., Imarisio, S., Ambrogio, C., Chiarle, R., et al. (2007). The Down syndrome critical region protein TTC3 inhibits neuronal differentiation via RhoA and Citron kinase. Journal of Cell Science, 120(11), 1859–1867.

3. Blandini, F., Sinforiani, E., Pacchetti, C., Samuele, A., Bazzini, E., Zangaglia, R., et al. (2006). Peripheral proteasome and caspase activity in Parkinson disease and Alzheimer disease. Neurology, 66(4), 529–534.

4. Brameier, M., Krings, A., & Maccallum, R. M. (2007). NucPred—Predicting nuclear localization of proteins. Bioinformatics, 23(9), 1159–1160.

5. Capkova, P., Misovicova, N., & Vrbicka, D. (2014). Partial trisomy and tetrasomy of chromosome 21 without Down Syndrome phenotype and short overview of genotype-phenotype correlation. A case report. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub, 158(2), 321–325.

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4. TTC3-Mediated Protein Quality Control, A Potential Mechanism for Cognitive Impairment;Cellular and Molecular Neurobiology;2021-02-27

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