Antisense Oligonucleotide Therapeutics for Neurodegenerative Disorders
Author:
Publisher
Springer Science and Business Media LLC
Subject
Geriatrics and Gerontology
Link
http://link.springer.com/content/pdf/10.1007/s13670-020-00341-7.pdf
Reference121 articles.
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2. Gao WY, Han FS, Storm C, Egan W, Cheng YC. Phosphorothioate oligonucleotides are inhibitors of human DNA polymerases and RNase H: implications for antisense technology. Mol Pharmacol. 1992;41(2):223–9.
3. • Bennett CF. Therapeutic antisense oligonucleotides are coming of age. Annu Rev Med. 2019;70:307–21. https://doi.org/10.1146/annurev-med-041217-010829Overview of ASO therapeutic strategies and pharmacology focused on clinically available agents.
4. Scoles DR, Pulst SM. Oligonucleotide therapeutics in neurodegenerative diseases. RNA Biol. 2018;15(6):707–14. https://doi.org/10.1080/15476286.2018.1454812.
5. • Egli M, Manoharan M. Re-engineering RNA molecules into therapeutic agents. Acc Chem Res. 2019;52(4):1036–47. https://doi.org/10.1021/acs.accounts.8b00650Detailed look at chemical modifications and their impact on nucleic acids as therapeutics.
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2. Towards Personalized Allele-Specific Antisense Oligonucleotide Therapies for Toxic Gain-of-Function Neurodegenerative Diseases;Pharmaceutics;2022-08-16
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