The effect of the monoamine oxidase inhibitor isocarboxazid on the canine metabolism of the cell-differentiating agent hexamethylene bisacetamide

Author:

Conley Barbara A.,Sewack Gerald F.,Egorin Merrill J.,Subramanyam Babu,Page John G.,Grieshaber Charles K.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference25 articles.

1. Callery PS, Egorin MJ, Geelhaar LA, Nayar MSB (1986) Identification of metabolites of the cell-differentiating agent hexamethylene bisacetamide in humans. Cancer Res 46:4900

2. Chun H, Leyland-Jones B, Hoth D, Shoemaker D, Wolpert-DeFilippes M, Grieshaber C, Cradock J, Davignon P, Moon R, Rifkind R, Wittes RE (1986) Hexamethylene bisacetamide: a polar-planar compound entering clinical trials as a differentiating agent. Cancer Treat Rep 70:991

3. Collins SJ, Bodner A, Ting R, Gallo RC (1980) Induction of morphological and functional differentiation of human promyelocytic leukemia cells (HL-60) by compounds which induce differentiation of murine leukemia cells. Int J Cancer 25:213

4. Conley BA, Callery PS, Egorin MJ, Subramanyam B, Geelhaar L, Pan S (1988) Involvement of monoamine oxidase and diamine oxidase in the metabolism of the cell differentiating agent hexamethylene bisacetamide (HMBA). Life Sci 43:793

5. Conley BA, Forrest A, Egorin MJ, Zuhowski EG, Sinibaldi V, Van Echo DA (1989) Phase I trial using adaptive control dosing of hexamethylene bisacetamide (NSC 95580). Cancer Res 49:3436

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