Whole-exome sequencing in maya indigenous families: variant in PPP1R3A is associated with type 2 diabetes

Author:

Sánchez-Pozos Katy,Ortíz-López María Guadalupe,Peña-Espinoza Bárbara I.,de los Ángeles Granados-Silvestre María,Jiménez-Jacinto Verónica,Verleyen Jérôme,Tekola-Ayele Fasil,Sanchez-Flores Alejandro,Menjivar Marta

Funder

PAPIIT-DGAPA

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,General Medicine

Reference52 articles.

1. American Diabetes Association (2015) (2) Classification and diagnosis of diabetes. Diabetes Care 38 (Suppl):S8–S16

2. Aschenbach WG, Suzuki Y, Breeden K, Prats C, Hirshman MF, Dufresne SD, Sakamoto K, Vilardo PG, Steele M, Kim JH, Jing SL, Goodyear LJ, DePaoli-Roach AA (2001) The muscle-specific protein phosphatase PP1G/R(GL)(G(M))is essential for activation of glycogen synthase by exercise. J Biol Chem 276:39959–39967

3. Chen MW, Yang MG, Wang CJ, Wang YM, Xu XP, Liu SQ, Zhang Q, Sun HY (2004a) Study on the association of PPP1R3 gene polymorphism with type 2 diabetes in Han population of Anhui province. Zhonghua Liu Xing Bing Xue Za Zhi 25:534–536

4. Chen MW, Yang MG, Wang CJ, Xu XP, Wang YM, Liu SQ, Zhang Q, Sun HY (2004b) Study on association of PPP1R3 gene 5 bp deletion/insertion within 3′-untranslated region polymorphism with type 2 diabetes. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 21:29–31

5. Choi Y, Sims GE, Murphy S, Miller JR, Chan AP (2012) Predicting the functional effect of amino acid substitutions and indels. PLoS One 7:e46688

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