Effect of Age-Related Factors on the Pharmacokinetics of Lamotrigine and Potential Implications for Maintenance Dose Optimisation in Future Clinical Trials-Reference-Cited by-同舟云学术

Effect of Age-Related Factors on the Pharmacokinetics of Lamotrigine and Potential Implications for Maintenance Dose Optimisation in Future Clinical Trials

Published:2018-01-23 Issue:8 Volume:57 Page:1039-1053
ISSN:0312-5963
Container-title:Clinical Pharmacokinetics
language:en
Short-container-title:Clin Pharmacokinet

Author:

van Dijkman Sven C.,de Jager Nico C. B.,Rauwé Willem M.,Danhof Meindert,Della Pasqua Oscar^ORCID

Funder

FP7 - European Union

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology

Link

http://link.springer.com/article/10.1007/s40262-017-0614-5/fulltext.html

Reference63 articles.

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2. Mullens EL. Clinical experience with lamotrigine monotherapy in adults with newly diagnosed epilepsy: a review of published randomised clinical trials. Clin Drug Investig. 1998;16(2):125–33.

3. Fitton A, Goa KL. Lamotrigine: An update of its pharmacology and therapeutic use in epilepsy. Drugs. 1995;50(4):691–713.

4. Brodie MJ, Richens A, Yuen A, UK, Lamotrigine/Carbamazepine Monotherapy Trial Group. Double-blind comparison of lamotrigine and carbamazepine in newly diagnosed epilepsy. Lancet. 1995;345(8948):476–9.

5. Italiano D, Perucca E. Clinical pharmacokinetics of new-generation antiepileptic drugs at the extremes of age: an update. Clin Pharmacokinet. 2013;52(8):627–45.

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