Determination of an Optimal Dosing Regimen for Fexinidazole, a Novel Oral Drug for the Treatment of Human African Trypanosomiasis: First-in-Human Studies

Author:

Tarral Antoine,Blesson Séverine,Mordt Olaf Valverde,Torreele Els,Sassella Daniela,Bray Michael A.,Hovsepian Lionel,Evène Eric,Gualano Virginie,Felices Mathieu,Strub-Wourgaft Nathalie

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology

Reference31 articles.

1. Brun R, Blum J, Chappuis F, Burri C. Human African trypanosomiasis. Lancet. 2010;375:148–59.

2. Barrett MP, Boykin DW, Brun R, Tidwell RR. Human African trypanosomiasis: pharmacological re-engagement with a neglected disease. Br J Pharmacol. 2007;152:1155–71.

3. Joubert J. Report of a WHO meeting on elimination of African trypanosomiasis (Trypanosoma brucei gambiense). Geneva, 3–5 December 2012. Geneva: WHO; 2013. p. 1754–824.

4. Hasker E, Lutumba P, Chappuis F, Kande V, Potet J, De Weggheleire A, et al. Human African trypanosomiasis in the Democratic Republic of the Congo: a looming emergency? PLoS Negl Trop Dis. 2012;6:e1950.

5. World Health Organization. Control and surveillance of human African trypanosomiasis: report of a WHO expert committee. WHO Technical Report Series 984. Geneva: WHO; 2013.

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