A Comprehensive Whole-Body Physiologically Based Pharmacokinetic Drug–Drug–Gene Interaction Model of Metformin and Cimetidine in Healthy Adults and Renally Impaired Individuals-Reference-Cited by-同舟云学术

A Comprehensive Whole-Body Physiologically Based Pharmacokinetic Drug–Drug–Gene Interaction Model of Metformin and Cimetidine in Healthy Adults and Renally Impaired Individuals

Published:2020-05-25 Issue:11 Volume:59 Page:1419-1431
ISSN:0312-5963
Container-title:Clinical Pharmacokinetics
language:en
Short-container-title:Clin Pharmacokinet

Author:

Hanke Nina,Türk Denise,Selzer Dominik,Ishiguro Naoki,Ebner Thomas,Wiebe Sabrina,Müller Fabian,Stopfer Peter,Nock Valerie,Lehr Thorsten^ORCID

Funder

Boehringer Ingelheim

Bundesministerium für Bildung und Forschung

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology

Link

https://link.springer.com/content/pdf/10.1007/s40262-020-00896-w.pdf

Reference54 articles.

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3. Vidon N, Chaussade S, Noel M, Franchisseur C, Huchet B, Bernier JJ. Metformin in the digestive tract. Diabetes Res Clin Pract. 1988;4:223–9. https://doi.org/10.1016/s0168-8227(88)80022-6.

4. Tucker GT, Casey C, Phillips PJ, Connor H, Ward JD, Woods HF. Metformin kinetics in healthy subjects and in patients with diabetes mellitus. Br J Clin Pharmacol. 1981;12:235–46. https://doi.org/10.1111/j.1365-2125.1981.tb01206.x.

5. Sambol NC, Chiang J, O’Conner M, Liu CY, Lin ET, Goodman AM, et al. Pharmacokinetics and pharmacodynamics of metformin in healthy subjects and patients with noninsulin-dependent diabetes mellitus. J Clin Pharmacol. 1996;36:1012–21. https://doi.org/10.1177/009127009603601105.

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