Determination of plasma and brain concentrations of SCH 39166 and their correlation to conditioned avoidance behavior in rats

Author:

Tedford Clark E.,Coffin Vicki L.,Ruperto Vilma,Cohen Mary,McQuade Robert D.,Johnson Richard,Kim Hong-Ki,Lin Chin-Chung

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology

Reference14 articles.

1. Barnett A, lorio LC, McQuade RM, Chipkin RE (1988) Pharmacological and behavioral effects of D1 dopamine antagonists. In: Goldstein, Fuxe, Tabachnick (eds) Central D1 dopamine receptors. Plenum, New York, pp. 137–144

2. Chipkin RE (1990) D1 antagonist in clinical trial. TIPS 11:185

3. Chipkin RE, lorio LC, Coffin VL, McQuade RD, Berger JG, Barnett A (1988) Pharmacological profile of SCH 39166: a dopamine D1 selective benzonaphthazepine with potential antipsychotic activity. J Pharmacol Exp Ther 247:1093–1102

4. Coffin VL, Latranyi MB, Chipkin RE (1989) Acute extrapyramidal syndrome in cebus monkeys: development mediated by dopamine D2 but not D1 receptors. J Pharmacol Exp Ther 249:769–774

5. Coffin VL, McHugh D, Chipkin RE, Barnett A (1992) SCH 39166, a potential antipsychotic drug, does not evoke movement disorders in cebus monkeys. Neurochem Int 20 [Suppl]: 141S-145S

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