Author:
Feng Ting,Xie Weiya,Xu Wenyi,Gao Ya,Liu Teng,Ta Dean,Qian Menglu,Cheng Qian
Abstract
AbstractBiomedical photoacoustics (PA) combines the advantages of selective optical absorption of biological tissues and high penetration depth of ultrasound, providing information on the macroscopic physiological structure and microscopic molecular level of biological tissues. Thus, it has great potential in the application of biomedical diagnosis. Among them, PA detection of bone is an important branch. In contrast to soft tissue, which can be regarded as a homogeneous medium, bone tissue is a two-phase complex medium (mineralized bone trabecular network in the solid phase and embedded bone marrow in the liquid phase), and this anisotropic and heterogeneous structure poses significant challenges to bone tissue characterization methods based on PA technology. This chapter introduces our work on PA detection for complex bone tissue, including the principle of PA wave generation and propagation, the methods of PA imaging and spectrum analysis, and their clinical applications. Finally, this chapter analyzes the current challenges in this field and anticipates future development trends based on the current research status of the PA technology.
Publisher
Springer Nature Switzerland
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