The development of BAY X 1005 and the Bayer series of leukotriene biosynthesis inhibitors
Author:
Publisher
Birkhäuser Basel
Link
http://link.springer.com/content/pdf/10.1007/978-3-0348-8703-8_17.pdf
Reference54 articles.
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2. Dixon RAF, Diehl RE, Opas E, Rands E, Vickers PJ, Evans JF, Gillard JW, Miller DK (1990) Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis. Nature 343: 282–284
3. Miller DK, Gillard JW, Vickers PJ, Sadowski S, Leveille C, Mancini JA, Charleson P, Dixon RA, Ford-Hutchinson AW, Fortin R et al (1990) Identification and isolation of a membrane protein necessary for leukotriene production. Nature 343: 278–281
4. Gillard J, Ford-Hutchinson AW, Chan C, Charleson S, Denis D, Foster A, Fortin R, Leger S, McFarlane CS, Morton H et al (1989) L-663,536 (MK-886) (3-[1-(4-chlorobenzyl)-3t-butyl-thio-5-isopropylindol-2-yll-2,2-dimethylpropanoic acid), a novel, orally active leukotriene biosynthesis inhibitor. Can J Physiol Pharmacol 67: 456–464
5. Lam BK, Penrose JF, Freeman GJ, Austen KF (1994) Expression cloning of a cDNA for human leukotriene C4 synthase, an integral menbrane protein conjugating reduced glutathione to leukotriene A4. Proc Natl Acad Sci USA 91: 7663–7667
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