Neuroprotection and Neurorestoration of Nigra Striatal Dopamine Neurons by Novel Multitarget Drugs, M30

Author:

Ben Ari Shunit,Youdim Moussa B. H.

Publisher

Springer International Publishing

Reference128 articles.

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2. Akao, Y., Maruyama, W., Shimizu, S., Yi, H., Nakagawa, Y., Shamoto-Nagai, M., Youdim, M. B., Tsujimoto, Y., & Naoi, M. (2002). Mitochondrial permeability transition mediates apoptosis induced by N-methyl(R)salsolinol, an endogenous neurotoxin, and is inhibited by Bcl-2 and rasagiline, N-propargyl-1(R)- aminoindan. Journal of Neurochemistry, 82, 913–923.

3. Amit, T., Avramovich-Tirosh, Y., Youdim, M. B., & Mandel, S. (2008). Targeting multiple Alzheimer’s disease etiologies with multimodal neuroprotective and neurorestorative iron chelators. The FASEB Journal, 22, 1296–305.

4. Avramovich-Tirosh, Y., Amit, T., Bar-Am, O., Zheng, H., Fridkin, M., & Youdim, M. B. (2007a). Therapeutic targets and potential of the novel brain-permeable multifunctional iron chelator-monoamine oxidase inhibitor drug, M-30, for the treatment of Alzheimer’ disease. Journal of Neurochemistry, 100, 490–502.

5. Avramovich-Tirosh, Y., Reznichenko, L., Mit, T., Zheng, H., Fridkin, M., Weinreb, O., Mandel, S., & Youdim, M. B. (2007b). Neurorescue activity, APP regulation and amyloid-beta peptide reduction by novel multi-functional brain permeable iron- chelating- antioxidants, M-30 and green tea polyphenol, EGCG. Current Alzheimer Research, 4, 403–411.

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