Studies on an Active Site residue, E177, That Affects Binding of the Coenzyme in D-Amino Acid Transaminase, and Mechanistic Studies on a Suicide Substrate-Reference-Cited by-同舟云学术

Studies on an Active Site residue, E177, That Affects Binding of the Coenzyme in D-Amino Acid Transaminase, and Mechanistic Studies on a Suicide Substrate

Published:2000 Issue: Volume: Page:339-346
ISSN:
Container-title:Biochemistry and Molecular Biology of Vitamin B6 and PQQ-dependent Proteins
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Author:

van Ophem Peter W.,Lepore Bryan W.,Kishimoto Kazuhisa,Ringe Dagmar,Manning James M.

Publisher

Birkhäuser Basel

Link

http://link.springer.com/content/pdf/10.1007/978-3-0348-8397-9_56

Reference10 articles.

1. Sugio, S., Petsko, G.A., Manning, J.M., Soda, K. and Ringe, D. (1995) Crystal Structure of a D-Amino Acid Aminotransferase: How the Protein Controls Stereoselectivity.Biochemistry34: 9661–9669.

2. Van Ophem, P.W., Peisach, D., Erickson, S.D., Soda, K., Ringe, D. and Manning, J.M. (1999) Effects of the E177K mutation in D-amino acid transaminase. Studies on an essential coenzyme anchoring group that contributes to stereochemical fidelity.Biochemistry38:1323–1331.

3. Van Ophem, P.W., Pospischil, M.A., Manning, J.M., Petsko, G.A., Peisach, D., Ringe, D. and Soda, K. (1995). Comparison of the Stability and Catalytic Ability of Two Recombinant Mutants of D-Amino Acid Transaminase Involved in Coenzyme Binding.Prot. Sci.4:2578–2586

4. Van Ophem, P.W., Erickson, S.D., Martinez del Pozo, A., Haller, I., Chait, B.T., Yoshimura, T., Soda, K., Ringe, D., Petsko, G. and Manning, J.M. (1998) Substrate Inhibition of D-Amino Acid Transaminase and Protection by Salts and by Reduced Nicotinamide Adenine Dinucleotide. Isolation and Initial Characterization of a Pyridoxo Intermediate Related to Inactivation.Biochemistry37:2879–2888.

5. Otwinowski, Z. and Minor, W. (1997) Processing of X-ray Diffraction Data Collected in Oscillation Mode.Methods Enzymol.276:307–326.