Author:
van Albada Sacha J.,Pronold Jari,van Meegen Alexander,Diesmann Markus
Abstract
AbstractWe are entering an age of ‘big’ computational neuroscience, in which neural network models are increasing in size and in numbers of underlying data sets. Consolidating the zoo of models into large-scale models simultaneously consistent with a wide range of data is only possible through the effort of large teams, which can be spread across multiple research institutions. To ensure that computational neuroscientists can build on each other’s work, it is important to make models publicly available as well-documented code. This chapter describes such an open-source model, which relates the connectivity structure of all vision-related cortical areas of the macaque monkey with their resting-state dynamics. We give a brief overview of how to use the executable model specification, which employs NEST as simulation engine, and show its runtime scaling. The solutions found serve as an example for organizing the workflow of future models from the raw experimental data to the visualization of the results, expose the challenges, and give guidance for the construction of an ICT infrastructure for neuroscience.
Publisher
Springer International Publishing
Reference53 articles.
1. Jordan, J., et al.: Extremely scalable spiking neuronal network simulation code: from laptops to exascale computers. Front. Neuroinform. 12, 2 (2018)
2. van Albada, S.J., et al.: Bringing anatomical information into neuronal network models. arXiv preprint arXiv:2007.00031 (2020)
3. Zilles, K., et al.: Architectonics of the human cerebral cortex and transmitter receptor fingerprints: reconciling functional neuroanatomy and neurochemistry. Eur. Neuropsychopharmacol. 12(6), 587–599 (2002)
4. Bakker, R., Thomas, W., Diesmann, M.: CoCoMac 2.0 and the future of tract-tracing databases. Front. Neuroinform. 6, 30 (2012)
5. Reimann, M.W., King, J.G., Muller, E.B., Ramaswamy, S., Markram, H.: An algorithm to predict the connectome of neural microcircuits. Front. Comput. Neurosci. 9, 120 (2015)
Cited by
6 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献