Erectile Dysfunction, Surgical and Regenerative Therapy

Abstract

AbstractErectile dysfunction (ED) is defined as the failure to achieve and/or maintain a penile erection that is satisfactory for sexual intercourse.The implantation of a penile prosthesis may be considered in patients who are not suitable for different pharmacotherapies and do not respond to the first and the second line of medical treatment.Intraoperative complications include hematoma formation, floppy glans, perforation of the corpora cavernosa, and urethral injury. Bladder, vascular, and bowel injury are the most dangerous events and should be prevented. Postoperative complications are represented by infections, erosions, and glandular ischemia.There is an increasing interest in the hypothesis of “regenerative” cures for ED aimed at decreasing fibrosis of the corpora cavernosa and rebuilding their normal biological architecture. These new regenerative treatments include stem cell injections, platelet-rich plasma, and low-intensity shock wave therapy.