Dakin−West Reaction
Author:
Publisher
Springer International Publishing
Link
http://link.springer.com/content/pdf/10.1007/978-3-030-50865-4_39
Reference15 articles.
1. Dakin, H. D.; West, R. J. Biol. Chem. 1928, 78, 91, 745, and 757. In 1928, Henry Dakin and Rudolf West, a clinician, reported on the reaction of α-amino acids with acetic anhydride to give α-acetamido ketones via azalactone intermediates. Interestingly, one year before this paper by Dakin and West, Levene and Steiger had observed both tyrosine and α-phenylananine gave “abnormal” products when acetylated under these conditions.2,3 Unfortunately, they were slow to identify the products and lost an opportunity to be immortalized by a name reaction.
2. Levene, P. A.; Steiger, R.E. J. Biol. Chem. 1928, 79, 95–103.
3. Wiley, R. H. Sci. 1950, 79, 95–103.
4. Buchanan, G. L. Chem. Soc. Rev. 1988, 17, 91–109. (Review).
5. Kawase, M.; Hirabayashi, M.; Koiwai, H.; Yamamoto, K.; Miyamae, H. Chem. Commun. 1998, 641–642.
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