The Effect of Metabolic Degradation on Radiotracer Design

Author:

Zolle I.,Halldin Ch.,Swahn C.-G.,Loc’h Ch.,Damani L. A.,Maziere B.

Publisher

Birkhäuser Basel

Reference9 articles.

1. Zolle I, Yu J, Robien W, Woloszczuk W, Höfer R. Biochemical Evaluation of Metyrapone Derivatives — Inhibition Kinetics and Affinity Studies. J. Labelled Compd. & Radiopharm. 1991; Vol. XXX: 420–422 (Abstract).

2. Zolle I, Woloszczuk W, Höfer R. Synthesis and in Vitro Evaluation of Metyrapone Derivatives as Potential Inhibitors of 11β-Hydroxylase Activity, In: Radiopharmaceuticals & Labelled Compounds 1984, IAEA Vienna, 1985: 337–342.

3. Yu J, Zolle I, Mertens J, Rakias F. Synthesis of 2-[131I]iodo-phenyl-metyrapone using Cu(I)-assisted nucleophilic exchange labelling: Study of the reaction conditions. Nucl Med Biol 1995; 22: 257–262.

4. Schirbel A, Coenen HH. Comparison of non-isotopic exchange methods for n.c.a. labelling of 2-iodophenyl-metyrapone. Nucl Med Biol 1995; 22: 1075–1079.

5. Zolle I, Halldin C, Yu J, Swahn CG. [11C]-2-Methoxyphenyl-metyrapone for PET. J Labelled Compd & Radiopharm 1993; Vol. XXXII: 547–549.

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