Eculizumab
Author:
Publisher
Springer Science and Business Media LLC
Subject
Nephrology
Link
http://link.springer.com/content/pdf/10.1007/s11560-011-0563-1.pdf
Reference10 articles.
1. Podack ER (1986) Molecular mechanisms of cytolysis by complement and by cytolytic lymphocytes. J Cell Biochem 30:133–170
2. Thomas TC, Rollins SA, Rother RP et al (1996) Inhibition of complement activity by humanized anti-C5 antibody and single-chain Fv. Mol Immunol 33:1389–1401
3. Hill A, Hillmen P, Richards SJ et al (2005) Sustained response and long-term safety of eculizumab in paroxysmal nocturnal hemoglobinuria. Blood 106:2559–2565
4. Hillmen P, Young NS, Schubert J et al (2006) The complement inhibitor eculizumab in paroxysmal nocturnal hemoglobinuria. N Engl J Med 355:1233–1243
5. Rother RP, Rollins SA, Mojcik CF et al (2007) Discovery and development of the complement inhibitor eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria. Nat Biotechnol 25:1256–1264
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