ƩexcessA1C index, the sum of yearly excess HbA1c values during the total period of diabetes, may have the potential to predict retinopathy by a linear regression setting regardless of duration in type 1 diabetes: a subgroup analysis of DCCT/EDIC data

Author:

Hirose AkiraORCID,Maeda Yasutaka,Goto Atsushi,Minami Masae,Kitano Shigehiko,Uchigata Yasuko

Publisher

Springer Science and Business Media LLC

Subject

Endocrinology, Diabetes and Metabolism,Internal Medicine

Reference8 articles.

1. Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group. Prolonged effect of intensive therapy on the risk of retinopathy complications in patients with type 1 diabetes mellitus: 10 years after the Diabetes Control and Complications Trial. Arch Ophthalmol. 2008;126(12):1707–15. https://doi.org/10.1001/archopht.126.12.1707.

2. Hirose A, Furushima D, Yamaguchi N, Kitano S, Uchigata Y. Prediction of retinopathy at 20 years after onset in younger-onset Type 1 diabetes using mean metabolic memory-free HbA1c values: the importance of using HbA1c data of total, not partial, diabetes duration. Diabetes Care. 2013;36(11):3812–4. https://doi.org/10.2337/dc13-0532.

3. Hainsworth DP, Bebu I, Aiello LP, et al. Risk factors for retinopathy in type 1 Diabetes: the DCCT/EDIC study. Diabetes Care. 2019;42(5):875–82. https://doi.org/10.2337/dc18-2308.

4. The Diabetes Control and Complications Trial Research Group. The effect of intensive diabetes treatment on the progression of diabetic retinopathy in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial. Arch Ophthalmol. 1995;113(1):36–51. https://doi.org/10.1001/archopht.1995.01100010038019.

5. Orchard TJ, Forrest KY, Ellis D, Becker DJ. Cumulative glycemic exposure and microvascular complications in insulin-dependent diabetes mellitus. The glycemic threshold revisited. Arch Intern Med. 1997;157(16):1851–6. https://doi.org/10.1001/archinte.1997.00440370091009.

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