Metformin: clinical topics and new mechanisms of action-Reference-Cited by-同舟云学术

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Metformin: clinical topics and new mechanisms of action

Published:2016-12-09 Issue:1 Volume:8 Page:4-6
ISSN:2190-1678
Container-title:Diabetology International
language:en
Short-container-title:Diabetol Int

Author:

Fujita Yoshihito,Inagaki Nobuya

Funder

Ministry of Education, Culture, Sports, Science, and Technology of Japan

Astellas Pharma Inc.

Taisho Toyama Pharmaceutical Co., Ltd.

Mitsubishi Tanabe Pharma Corporation

Takeda Pharmaceutical Company Limited.

Daiichi Sankyo Company, Limited.

MSD

Sanofi

Dainippon Sumitomo Pharma Co., Ltd.

Kyowa Hakko Kirin Co., Ltd.

Eli Lilly Japan K.K.

Shiratori Pharmaceutical Co., Ltd.

Ono Pharmaceutical Co., Ltd.

JT

Pfizer

Nippon Boehringer Ingelheim Co., Ltd.

Sanwa Kagaku Kenkyusho Co., Ltd.

Kissei Pharmaceutical Co., Ltd.

Japan Diabetes Foundation

AstraZeneca

Publisher

Springer Science and Business Media LLC

Subject

Endocrinology, Diabetes and Metabolism,Internal Medicine

Link

http://link.springer.com/content/pdf/10.1007/s13340-016-0300-0.pdf

Reference29 articles.

1. Inzucchi SE, Bergenstal RM, Buse JB, et al. Management of hyperglycemia in type 2 diabetes, 2015: a patient-centered approach: update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care. 2015;38:140–9.

2. Rojas LB, Gomes MB. Metformin: an old but still the best treatment for type 2 diabetes. Diabetol Metab Syndr. 2013; 5:6.

3. Pryor R, Cabreiro F. Repurposing metformin: an old drug with new tricks in its binding pockets. Biochem J. 2015;471:307–22.

4. El-Mir MY, Nogueira V, Fontaine E, et al. Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I. J Biol Chem. 2000; 275:223–28.

5. Owen MR, Doran E, Halestrap AP. Evidence that metformin exerts its antidiabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain. Biochem J. 2000;348:607–14.

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