Myeloablative intravenous busulfan-containing regimens for allo-HSCT in AML or MDS patients over 54 years old: combined results of three phase II studies

Author:

Uchida NaoyukiORCID,Matsumoto Kana,Sakura Toru,Hidaka Michihiro,Miyamoto Toshihiro,Eto Tetsuya,Maeda Yoshinobu,Murayama Tohru,Fujishima Naohito,Yoshimoto Goichi,Morita Kunihiko,Kishimoto Junji,Teshima Takanori,Taniguchi Shuichi,Yamashita Takuya,Mori Shin-ichiro,Akashi Koichi,Harada Mine,

Funder

The Japanese Ministry of Health, Labour and Welfare

The Research Foundation for Community Medicine

Publisher

Springer Science and Business Media LLC

Subject

Hematology

Reference63 articles.

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2. McSweeney PA, Niederwieser D, Shizuru JA, Sandmaier BM, Molina AJ, Maloney DG, et al. Hematopoietic cell transplantation in older patients with hematologic malignancies: replacing high-dose cytotoxic therapy with graft-versus-tumor effects. Blood. 2001;97(11):3390–400.

3. Slavin S, Nagler A, Naparstek E, Kapelushnik Y, Aker M, Cividalli G, et al. Nonmyeloablative stem cell transplantation and cell therapy as an alternative to conventional bone marrow transplantation with lethal cytoreduction for the treatment of malignant and nonmalignant hematologic diseases. Blood. 1998;91(3):756–63.

4. Lim Z, Brand R, Martino R, van Biezen A, Finke J, Bacigalupo A, et al. Allogeneic hematopoietic stem-cell transplantation for patients 50 years or older with myelodysplastic syndromes or secondary acute myeloid leukemia. J Clin Oncol. 2010;28(3):405–11.

5. Aoudjhane M, Labopin M, Gorin NC, Shimoni A, Ruutu T, Kolb HJ, et al. Comparative outcome of reduced intensity and myeloablative conditioning regimen in HLA identical sibling allogeneic haematopoietic stem cell transplantation for patients older than 50 years of age with acute myeloblastic leukaemia: a retrospective survey from the Acute Leukemia Working Party (ALWP) of the European group for Blood and Marrow Transplantation (EBMT). Leukemia. 2005;19(12):2304–12.

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