Effect of haplotypes of functional SNPs related to expression of fetal hemoglobin (HbF) on clinical prognosis of hematological malignancies
Author:
Funder
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Publisher
Springer Science and Business Media LLC
Subject
Hematology
Link
https://link.springer.com/content/pdf/10.1007/s12185-023-03570-6.pdf
Reference5 articles.
1. Hara R, Kitahara T, Numata H, Toyosaki M, Watanabe S, Kikkawa E, et al. Fetal hemoglobin level predicts lower-risk myelodysplastic syndrome. Int J Hematol. 2022. https://doi.org/10.1007/s12185-022-03523-5.
2. Sales RR, Belisario AR, Faria G, Mendes F, Luizon MR, Viana MB. Functional polymorphisms of BCL11A and HBS1L-MYB genes affect both fetal hemoglobin level and clinical outcomes in a cohort of children with sickle cell anemia. Ann Hematol. 2020;99(7):1453–63. https://doi.org/10.1007/s00277-020-04079-2.
3. Sales RR, Nogueira BL, Belisario AR, Faria G, Mendes F, Viana MB, et al. Fetal hemoglobin-boosting haplotypes of BCL11A gene and HBS1L-MYB intergenic region in the prediction of clinical and hematological outcomes in a cohort of children with sickle cell anemia. J Hum Genet. 2022;67(12):701–9. https://doi.org/10.1038/s10038-022-01079-0.
4. Bauer DE, Orkin SH. Hemoglobin switching’s surprise: the versatile transcription factor BCL11A is a master repressor of fetal hemoglobin. Curr Opin Genet Dev. 2015;33:62–70. https://doi.org/10.1016/j.gde.2015.08.001.
5. Sales RR, Nogueira BL, Tosatti JAG, Gomes KB, Luizon MR. Do genetic polymorphisms affect fetal hemoglobin (HbF) levels in patients with sickle cell anemia treated with hydroxyurea? A systematic review and pathway analysis. Front Pharmacol. 2022. https://doi.org/10.3389/fphar.2021.779497.
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