A metabolite of buspirone increases locus coeruleus activity via alpha2-receptor blockade
Author:
Publisher
Springer Science and Business Media LLC
Subject
Biological Psychiatry,Psychiatry and Mental health,Neurology (clinical),Neurology
Link
http://link.springer.com/content/pdf/10.1007/BF01578749.pdf
Reference44 articles.
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3. Aston-Jones G, Bloom FE (1981 a) Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle. J Neurosci 1: 879–886
4. Aston-Jones G, Bloom FE (1981 b) Norepinephrine-containing locus coeruleus neurons in behaving rats exhibit pronounced responses to non-noxious environment stimuli. J Neurosci 1: 887–900
5. Caccia S, Muglia M, Mancinelli A, Garattini S (1983) Disposition and metabolism of buspirone and its metabolite 1-(2-pyrimidinyl)-piperazine in the rat. Xenobiotica 13: 147–153
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