Characterization of the von Willebrand factor/factor VIII complex produced by a novel purification process
Author:
Publisher
Springer Science and Business Media LLC
Subject
Organic Chemistry,Drug Discovery,Molecular Medicine
Link
https://link.springer.com/content/pdf/10.1007/s12272-020-01245-y.pdf
Reference30 articles.
1. Aledort L, Ljung R, Mann K, Pipe S (2014) Factor VIII therapy for hemophilia A: current and future issues. Expert Rev Hematol 7:373–385. https://doi.org/10.1586/17474086.2014.899896
2. Bravo MI, Da Rocha-Souto B, Grancha S, Jorquera JI (2014) Native plasma-derived FVIII/VWF complex has lower sensitivity to FVIII inhibitors than the combination of isolated FVIII and VWF proteins. Impact on Bethesda assay titration of FVIII inhibitors. Haemophilia 20:905–911. https://doi.org/10.1111/hae.12494
3. Bravo MI, Ortiz AM, Costa M, Grancha S, Jorquera JI (2016) Neutralizing capacity of inhibitors on FVIII is lower for natural FVIII/VWF complex than for isolated FVIII: in vitro comparative study in eleven different therapeutic FVIII concentrates. Haemophilia 22:e301–e348. https://doi.org/10.1111/hae.12975
4. Budde U, Metzner HJ, Müller HG (2006) Comparative analysis and classification of Von Willebrand factor/factor VIII concentrates: impact on treatment of patients with Von Willebrand disease. Semin Thromb Hemost 32:626–635. https://doi.org/10.1055/s-2006-949668
5. Burnouf T, Radosevich M (2001) Affinity chromatography in the industrial purification of plasma proteins for therapeutic use. J Biochem Biophys Methods 49:575–586. https://doi.org/10.1016/S0165-022X(01)00221-4
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