Novel small molecule Raf kinase inhibitors for targeted cancer therapeutics
-
Published:2012-04
Issue:4
Volume:35
Page:605-615
-
ISSN:0253-6269
-
Container-title:Archives of Pharmacal Research
-
language:en
-
Short-container-title:Arch. Pharm. Res.
Author:
Kim Do-Hee,Sim Taebo
Publisher
Springer Science and Business Media LLC
Subject
Organic Chemistry,Drug Discovery,Molecular Medicine
Reference72 articles.
1. Ahmad, T. and Eisen, T., Kinase inhibition with BAY 43-9006 in renal cell carcinoma. Clin. Cancer Res., 10, 6388S–6392S (2004). 2. Ahnstedt, H., Saveland, H., Nilsson, O., and Edvinsson, L., Human cerebrovascular contractile receptors are upregulated via a B-Raf/MEK/ERK-sensitive signaling pathway. BMC Neurosci., 12, 5 (2011). 3. Amiri, P., Aikawa, M. E., Dove, J., Stuart, D. D., Poon, D., Pick, T., Ramurthy, S., Subramanian, S., Levine, B., Costales, A., Harris, A., and Paul, R., CHIR-265 is a potent selective inhibitor of c-Raf/B-Raf/mutB-Raf that effectively inhibits proliferation and survival of cancer cell lines with Ras/Raf pathway mutations. AACR Meeting Abstracts, 2006, 1140a (2006). 4. Auclair, D., Miller, D., Yatsula, V., Pickett, W., Carter, C., Chang, Y., Zhang, X., Wilkie, D., Burd, A., Shi, H., Rocks, S., Gedrich, R., Abriola, L., Vasavada, H., Lynch, M., Dumas, J., Trail, P. A., and Wilhelm, S. M., Antitumor activity of sorafenib in FLT3-driven leukemic cells. Leukemia, 21, 439–445 (2007). 5. Bollag, G., Hirth, P., Tsai, J., Zhang, J., Ibrahim, P. N., Cho, H., Spevak, W., Zhang, C., Zhang, Y., Habets, G., Burton, E. A., Wong, B., Tsang, G., West, B. L., Powell, B., Shellooe, R., Marimuthu, A., Nguyen, H., Zhang, K. Y., Artis, D. R., Schlessinger, J., Su, F., Higgins, B., Iyer, R., D’andrea, K., Koehler, A., Stumm, M., Lin, P. S., Lee, R. J., Grippo, J., Puzanov, I., Kim, K. B., Ribas, A., Mcarthur, G. A., Sosman, J. A., Chapman, P. B., Flaherty, K. T., Xu, X., Nathanson, K. L., and Nolop, K., Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma. Nature, 467, 596–599 (2010).
Cited by
32 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
|
|