Death-associated protein kinase 1 phosphorylates MDM2 and inhibits its protein stability and function
Author:
Funder
National Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC
Subject
Organic Chemistry,Drug Discovery,Molecular Medicine
Link
https://link.springer.com/content/pdf/10.1007/s12272-023-01469-8.pdf
Reference50 articles.
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2. Chen HY, Lee YR, Chen RH (2014) The functions and regulations of DAPK in cancer metastasis. Apoptosis 19(2):364–370. https://doi.org/10.1007/s10495-013-0923-6
3. Chen D, Zhou XZ, Lee TH (2019) Death-associated protein kinase 1 as a promising drug target in cancer and Alzheimer’s disease. Recent Pat Anticancer Drug Discov 14(2):144–157. https://doi.org/10.2174/1574892814666181218170257
4. Chen D, Mei Y, Kim N, Lan G, Gan CL, Fan F, Zhang T, Xia Y, Wang L, Lin C, Ke F, Zhou XZ, Lu KP, Lee TH (2020) Melatonin directly binds and inhibits death-associated protein kinase 1 function in Alzheimer’s disease. J Pineal Res 69(2):e12665. https://doi.org/10.1111/jpi.12665
5. Chen D, Lan G, Li R, Mei Y, Shui X, Gu X, Wang L, Zhang T, Gan CL, Xia Y, Hu L, Tian Y, Zhang M, Lee TH (2022) Melatonin ameliorates tau-related pathology via the miR-504-3p and CDK5 axis in Alzheimer’s disease. Transl Neurodegener 11(1):27. https://doi.org/10.1186/s40035-022-00302-4
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