Enhanced bioavailability and hepatoprotective effect of silymarin by preparing silymarin-loaded solid dispersion formulation using freeze-drying method-Reference-Cited by-同舟云学术

Enhanced bioavailability and hepatoprotective effect of silymarin by preparing silymarin-loaded solid dispersion formulation using freeze-drying method

Published:2022-09-30 Issue:10 Volume:45 Page:743-760
ISSN:0253-6269
Container-title:Archives of Pharmacal Research
language:en
Short-container-title:Arch. Pharm. Res.

Author:

Lim Dong Yu,Pang Minyeong,Lee Jaehyeok,Lee Jihoon,Jeon Ji-Hyeon,Park Jin-Hyang,Choi Min-Koo,Song Im-Sook^ORCID

Funder

National Research Foundation of Korea

Publisher

Springer Science and Business Media LLC

Subject

Organic Chemistry,Drug Discovery,Molecular Medicine

Link

https://link.springer.com/content/pdf/10.1007/s12272-022-01407-0.pdf

Reference36 articles.

1. Adhikari M, Arora R (2015) Nano-silymarin provides protection against γ-radiation-induced oxidative stress in cultured human embryonic kidney cells. Mutat Res Genet Toxicol Environ Mutagen 792:1–11. https://doi.org/10.1016/j.mrgentox.2015.08.006

2. Basaga H, Poli G, Tekkaya C, Aras I (1997) Free radical scavenging and antioxidative properties of “silibin” complexes on microsomal lipid peroxidation. Cell Biochem Funct 15:27–33. https://doi.org/10.1002/(SICI)1099-0844(199703)15:1%3c27::AID-CBF714%3e3.0.CO;2-W

3. Cid AG, Simonazzi A, Palma SD, Bermúdez JM (2019) Solid dispersion technology as a strategy to improve the bioavailability of poorly soluble drugs. Ther Deliv 10:363–382. https://doi.org/10.4155/tde-2019-0007

4. Deng JW, Shon JH, Shin HJ, Park SJ, Yeo CW, Zhou HH, Song IS, Shin JG (2008) Effect of silymarin supplement on the pharmacokinetics of rosuvastatin. Pharm Res 25:1807–1814. https://doi.org/10.1007/s11095-007-9492-0

5. Di Costanzo A, Angelico R (2019) Formulation strategies for enhancing the bioavailability of silymarin: the state of the art. Molecules 24:2155. https://doi.org/10.3390/molecules24112155

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