Suppression of adipocyte differentiation by 15-methoxypinusolidic acid through inhibition of PPARγ activity
Author:
Publisher
Springer Science and Business Media LLC
Subject
Organic Chemistry,Drug Discovery,Molecular Medicine
Link
http://link.springer.com/content/pdf/10.1007/s12272-010-0709-0.pdf
Reference38 articles.
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2. Armoni, M., Kritz, N., Harel, C., Bar-Yoseph, F., Chen, H., Quon, M. J., and Karnieli, E., Peroxisome proliferators-activated receptor-gamma represses GLUT4 promoter activity in primary adipocytes, and rosiglitazone alleviates this effect. J. Biol. Chem., 278, 30614–30623 (2003).
3. Chilliard, Y., Ferlay, A., Faulconnier, Y., Bonnet, M., Rouel, J., and Bocquier, F., Adipose tissue metabolism and its role in adaptations to undernutrition in ruminants. Proc. Nutr. Soc., 59, 127–134 (2000).
4. Choi, Y., Moon, A., and Kim, Y. C., A pinusolide derivative, 15-methoxypinusolidic acid from Biota orientalis inhibits inducible nitric oxide synthase in microglial cells: implication for a potential anti-inflammatory effect. Int. Immunopharmacol., 8, 548–555 (2008).
5. Chui, P. C., Guan, H. P., Lehrke, M., and Lazar, M. A., PPARgamma regulates adipocyte cholesterol metabolism via oxidized LDL receptor 1. J. Clin. Invest., 115, 2244–2256 (2005).
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