Metformin mitigates renal dysfunction in obese insulin-resistant rats via activation of the AMPK/PPARα pathway-Reference-Cited by-同舟云学术

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Metformin mitigates renal dysfunction in obese insulin-resistant rats via activation of the AMPK/PPARα pathway

Published:2023-03-26 Issue:5 Volume:46 Page:408-422
ISSN:0253-6269
Container-title:Archives of Pharmacal Research
language:en
Short-container-title:Arch. Pharm. Res.

Author:

Thongnak Laongdao,Pengrattanachot Nattavadee,Promsan Sasivimon,Phengpol Nichakorn,Sutthasupha Prempree,Jaikumkao Krit,Lungkaphin Anusorn^ORCID

Funder

National Research Council of Thailand

Functional Foods for Health and Disease, Faculty of Medicine, Chiang Mai University

Faculty of Medicine, Chiang Mai University

Functional Food Research Center for Well-being, Chiang Mai University

Chiang Mai University

Publisher

Springer Science and Business Media LLC

Subject

Organic Chemistry,Drug Discovery,Molecular Medicine

Link

https://link.springer.com/content/pdf/10.1007/s12272-023-01439-0.pdf

Reference41 articles.

1. Abdelkader NF, Elbaset MA, Moustafa PE, Ibrahim SM (2022) Empagliflozin mitigates type 2 diabetes-associated peripheral neuropathy: a glucose-independent effect through AMPK signaling. Arch Pharm Res 45:475–493. https://doi.org/10.1007/s12272-022-01391-5

2. Arruda AC, Perilhao MS, Santos WA, Gregnani MF, Budu A, Neto JCR, Estrela GR, Araujo RC (2020) PPARalpha-dependent modulation by metformin of the expression of OCT-2 and MATE-1 in the kidney of mice. Molecules. https://doi.org/10.3390/molecules25020392

3. Bai F, Liu Y, Tu T, Li B, Xiao Y, Ma Y, Qin F, Xie J, Zhou S, Liu Q (2019) Metformin regulates lipid metabolism in a canine model of atrial fibrillation through AMPK/PPAR-alpha/VLCAD pathway. Lipids Health Dis 18:109. https://doi.org/10.1186/s12944-019-1059-7

4. Burri L, Thoresen GH, Berge RK (2010) The role of PPARalpha activation in liver and muscle. PPAR Res 2010. https://doi.org/10.1155/2010/542359

5. Ceja-Galicia ZA, Garcia-Arroyo FE, Aparicio-Trejo OE, El-Hafidi M, Gonzaga-Sanchez G, Leon-Contreras JC, Hernandez-Pando R, Guevara-Cruz M, Tovar AR, Rojas-Morales P, Aranda-Rivera AK, Sanchez-Lozada LG, Tapia E, Pedraza-Chaverri J (2022) Therapeutic effect of curcumin on 5/6Nx Hypertriglyceridemia: association with the improvement of renal mitochondrial beta-oxidation and lipid metabolism in kidney and liver. Antioxidants 11(11):2195. https://doi.org/10.3390/antiox11112195

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