Effect of particle size on the dissolution behaviors of poorly water-soluble drugs

Author:

Chu Kyung Rok,Lee Eunhee,Jeong Seong Hoon,Park Eun-Seok

Publisher

Springer Science and Business Media LLC

Subject

Organic Chemistry,Drug Discovery,Molecular Medicine

Reference21 articles.

1. Anderberg, E. K., Studies on the dissolution of fine particulate practically insoluble drugs and on the effect of surface active enhancers on gastrointestinal absorption of hydrophilic drugs. Acta Univ. Ups., 91, 8 (1992).

2. Bisrat, M. and Nyström, C., Physicochemical aspects of drug release: VIII. The relation between particle size and surface specific dissolution rate in agitated suspensions. Int. J. Pharm., 47, 223–231 (1988).

3. Brockmeier, D., In vitro/in vivo correlation of dissolution using moments of dissolution and transit times. Acta Pharm. Technol., 32, 164–174 (1986).

4. Brunner, E., Theorie der Reaktionsgeschwindigkeit in heterogenen systemen. Z. Phys. Chem. (N F), 47, 56–102 (1904).

5. Buckton, G., Characterization of small changes in the physical properties of powders of significance for dry powder inhaler formulations. Adv. Drug Deliv. Rev., 26, 17–27 (1997).

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