Four-week administration of nimesulide, a cyclooxygenase-2 inhibitor, improves endothelial dysfunction in the hindlimb vasculature of streptozotocin-induced diabetic rats
Author:
Publisher
Springer Science and Business Media LLC
Subject
Organic Chemistry,Drug Discovery,Molecular Medicine
Link
http://link.springer.com/content/pdf/10.1007/s12272-001-2155-5.pdf
Reference24 articles.
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2. Bardal, S., Misurski, D., Qiu, X., Desai, K., and McNeill, J. R., Chronic treatment with vascular endothelial growth factor preserves agonist-evoked vascular responses in the streptozotocin-induced diabetic rat. Diabetologia, 49, 811–818 (2006).
3. Bulut, D., Liaghat, S., Hanefeld, C., Koll, R., Miebach, T., and Mugge, A., Selective cyclooxygenase-2 inhibition with parecoxib acutely impairs endothelium-dependent vasodilatation in patients with essential hypertension. J. Hypertens., 21, 1663–1667 (2003).
4. Calles-Escandon, J. and Cipolla, M., Diabetes and endothelial dysfunction: A clinical perspective. Endocr. Rev., 22, 36–52 (2001).
5. Calver, A., Collier, J., and Vallance, P., Inhibition and stimulation of nitric oxide synthesis in the human forearm arterial bed of patients with insulin-dependent diabetes. J. Clin. Invest., 90, 2548–2554 (1992).
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