In Vivo Models for the Evaluation of Antithrombotics and Thrombolytics

Author:

Mousa Shaker A.

Publisher

Humana Press

Reference289 articles.

1. Didisheim, P. (1972) Animal models useful in the study of thrombosis and antithrombotic agents Prog Hemost Thromb 1, 165–97.

2. Leadley, R.J., Jr., Chi, L., Rebello, S.S., and Gagnon, A. (2000) Contribution of in vivo models of thrombosis to the discovery and development of novel antithrombotic agents J Pharmacol Toxicol Methods 43, 101–16.

3. Wessler, S., Reimer, S.M., and Sheps, M.C. (1959) Biologic assay of a thrombosis-inducing activity in human serum J Appl Physiol 14, 943–6.

4. Meuleman, D.G., Hobbelen, P.M., Van Dinther, T.G., Vogel, G.M., Van Boeckel, C.A., and Moelker, H.C. (1991) Antifactor Xa activity and antithrombotic activity in rats of structural analogues of the minimum antithrombin III binding sequence: discovery of compounds with a longer duration of action than of the natural pentasaccharide Semin Thromb Hemost 17 (Suppl 1), 112–7.

5. Carrie, D., Caranobe, C., Saivin, S., Houin, G., Petitou, M., Lormeau, J.C., Van Boeckel, C., Meuleman, D., and Boneu, B. (1994) Pharmacokinetic and antithrombotic properties of two pentasaccharides with high affinity to antithrombin III in the rabbit: comparison with CY216 Blood 84, 2571–7.

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