TREMble Before TREM2: The Mighty Microglial Receptor Conferring Neuroprotective Properties in TDP-43 Mediated Neurodegeneration
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Medicine,Physiology,General Neuroscience
Link
https://link.springer.com/content/pdf/10.1007/s12264-022-00944-4.pdf
Reference15 articles.
1. Hickman S, Izzy S, Sen P, Morsett L, El Khoury J. Microglia in neurodegeneration. Nat Neurosci 2018, 21: 1359–1369.
2. Zhao Y, Wu X, Li X, Jiang LL, Gui X, Liu Y. TREM2 is a receptor for β-amyloid that mediates microglial function. Neuron 2018, 97: 1023-1031.e7.
3. Guerreiro R, Wojtas A, Bras J, Carrasquillo M, Rogaeva E, Majounie E, et al. TREM2 variants in Alzheimer’s disease. N Engl J Med 2013, 368: 117–127.
4. Xie M, Liu YU, Zhao S, Zhang L, Bosco DB, Pang YP, et al. TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration. Nat Neurosci 2022, 25: 26–38.
5. Ganguly D, Haak S, Sisirak V, Reizis B. The role of dendritic cells in autoimmunity. Nat Rev Immunol 2013, 13: 566–577.
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