ESCAPE-NA1 Trial Brings Hope of Neuroprotective Drugs for Acute Ischemic Stroke: Highlights of the Phase 3 Clinical Trial on Nerinetide
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Medicine,Physiology,General Neuroscience
Link
https://link.springer.com/content/pdf/10.1007/s12264-020-00627-y.pdf
Reference9 articles.
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3. Howells DW, Porritt MJ, Rewell SS, O’Collins V, Sena ES, van der Worp HB et al. Different strokes for different folks: the rich diversity of animal models of focal cerebral ischemia. J Cereb Blood Flow Metab 2010, 30: 1412–1431.
4. Hill MD, Goyal M, Menon BK, Nogueira RG, McTaggart RA, Demchuk AM et al. Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial. Lancet 2020, 395: 878–887.
5. Cook DJ, Teves L, Tymianski M. Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain. Nature 2012, 483: 213–217.
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