Up-Regulation of Akt and Nav1.8 in BmK I-Induced Pain-Reference-Cited by-同舟云学术

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Up-Regulation of Akt and Nav1.8 in BmK I-Induced Pain

Published:2018-03-27 Issue:3 Volume:34 Page:539-542
ISSN:1673-7067
Container-title:Neuroscience Bulletin
language:en
Short-container-title:Neurosci. Bull.

Author:

Zhou Guokun,Jiao Yunlu,Zhou You,Qin Shichao,Tao Jie,Jiang Feng,Tan Zhi-Yong,Ji Yong-Hua

Publisher

Springer Science and Business Media LLC

Subject

General Medicine,Physiology,General Neuroscience

Link

http://link.springer.com/article/10.1007/s12264-018-0222-x/fulltext.html

Reference7 articles.

1. Ye P, Hua L, Jiao Y, Li Z, Qin S, Fu J, et al. Functional up-regulation of Nav1.8 sodium channel on dorsal root ganglia neurons contributes to the induction of scorpion sting pain. Acta Biochim Biophys Sin (Shanghai) 2016, 48: 132–144.

2. Liu HX, Liu GX, Bi YW. CNTF regulates neurite outgrowth and neuronal migration through JAK2/STAT3 and PI3K/Akt signaling pathways of DRG explants with gp120-induced neurotoxicity in vitro. Neurosci Lett 2014, 569: 110–115.

3. Liu Z, Cai H, Zhang P, Li H, Liu H, Li Z. Activation of ERK1/2 and PI3K/Akt by IGF-1 on GAP-43 expression in DRG neurons with excitotoxicity induced by glutamate in vitro. Cell Mol Neurobiol 2012, 32: 191–200.

4. Xu Q, Fitzsimmons B, Steinauer J, O’Neill A, Newton AC, Hua XY, et al. Spinal phosphinositide 3-kinase-Akt-mammalian target of rapamycin signaling cascades in inflammation-induced hyperalgesia. J Neurosci 2011, 31: 2113–2124.

5. Choi JIL, Koehrn FJ, Sorkin LS. Carrageenan induced phosphorylation of Akt is dependent on neurokinin-1 expressing neurons in the superficial dorsal horn. Mol Pain 2012, 8: 4.

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1. Spider and scorpion knottins targeting voltage-gated sodium ion channels in pain signaling;Biochemical Pharmacology;2024-09

2. Dezocine relieves the postoperative hyperalgesia in rats through suppressing the hyper-action of Akt1/GSK-3β pathway;Experimental Brain Research;2022-03-25

3. Scorpion Toxins from Buthus martensii Karsch (BmK) as Potential Therapeutic Agents for Neurological Disorders: State of the Art and Beyond;Medical Toxicology;2021-02-03

4. Pain-related toxins in scorpion and spider venoms: a face to face with ion channels;Journal of Venomous Animals and Toxins including Tropical Diseases;2021

5. Up-regulation of P2X7 Receptors Contributes to Spinal Microglial Activation and the Development of Pain Induced by BmK-I;Neuroscience Bulletin;2019-02-28

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