Canine digitalis arrhythmia as a model for detecting Na-channel blocking antiarrhythmic drugs: A comparative study using other canine arrhythmia models and the new antiarrhythmic drugs, propafenone, tocainide, and SUN 1165

Author:

Hashimoto Keitaro,Ishii Masaaki,Komori Sadayoshi,Mitsuhashi Harumi

Publisher

Springer Science and Business Media LLC

Subject

Cardiology and Cardiovascular Medicine

Reference25 articles.

1. Vaughan Williams EM (1974) Electrophysiological basis for a rational approach to antidysrhythmic drug therapy. In: Harper NJ, Simmonds AB (eds) Advances in drug research, vol. 9. Academic Press, London, pp 69–101

2. Hashimoto K, Satoh H, Shibuya T, Imai S (1982) Canine-effective plasma concentrations of antiarrhythmic drugs on the two-stage coronary ligation arrhythmia. J Pharmacol Exp Ther 223: 801–810

3. Hashimoto K, Shibuya T, Satoh H, Imai S (1983) Quantitative analysis of the antiarrhythmic effect of drugs on canine ventricular arrhythmias by the determination of minimum effective plasma concentrations. Jpn Circ J 47: 92–97

4. Shibuya T, Hashimoto K, Imai S (1983) Effective plasma concentrations of antiarrhythmic drugs against sustained halothane-adrenaline arrhythmia in dogs. J Cardiovasc Pharmacol 5: 538–545

5. Hashimoto K, Komori S, Ishii M, Kamiya J (1984) Effective plasma concentrations of aprindine in canine ventricular arrhythmias. J Cardiovasc Pharmacol 6: 12–19

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