Activation of 2?,5?-oligoadenylate synthetase and B-2 microglobulin in cancer patients treated with partially pure gamma interferon: Dependence of biological effect on administration route

Author:

Rosenblum Michel G.,Riso Adan,Gutterman Jordan U.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference23 articles.

1. Borden EC, Ball LA (1981) Interferons: Biochemical, cell growth, inhibitory and immunological effects. Prog Hematol 350:299

2. Braude I (1983a) A simple and efficient method for the purification of human gamma interferon. Prep Biochem 13 (3):177

3. Braude I (1983b) A simple and efficient method for the production of human gamma interferon. J Immunol Methods 63:237

4. Chapekar MS, Glazer RI (1984) Effects of human immune interferon on cell viability, (2?,5?)oligoadenylate synthesis, and polyamine-dependent protein phosphorylation in human colon carcinoma cells in vitro. Cancer Res 44:2144

5. Gutterman JU, Bleumenschein GR, Alexanian R, Yap H-Y, Buzdar AU, Cabanillas F, Hortobagyi GN, Hersh EM, Rasmussen SL, Harmon M, Kramer M, Pestka S (1981) Leukocyte interferon-induced tumor regression in human metastatic breast cancer, multiple myeloma, and malignant lymphoma. Ann Intern Med 93:399

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