Author:
Pallanti Stefano,Di Ponzio Michele,Levola Jonna,Lioumis Pantelis,Paunio Tiina,Kičić Dubravko,Ilmoniemi Risto,Makris Nikos
Abstract
AbstractBehavioral addictions (BA) and substance use disorders (SUDs) share core features, including impaired control and craving, leading to significant personal and societal impacts. Previous research has identified the pre-supplementary motor area (pre-SMA) as a critical node in GD-related neurocircuitry, making it a potential target for interventions also in SUDs. Theta-burst stimulation (TBS) offers a non-invasive method to modulate pre-SMA activity. This study included 58 participants diagnosed with GD or SUDs. They underwent bilateral pre-SMA continuous TBS (cTBS) sessions targeting craving, impulsivity, and addiction severity. Standardized scales and questionnaires were employed to assess the outcomes. cTBS parameters included 20 daily sessions with 80% resting motor threshold (RMT). Both GD and SUD groups exhibited significant reductions in addiction severity and craving following cTBS. Impulsivity decreased significantly in SUD but not in GD. The study’s findings underscore the potential of pre-SMA TBS as an adjunctive treatment for GD and SUDs. The observed improvements in addiction severity and craving emphasize the shared neuronal mechanisms underlying these disorders. However, the nuanced differences, especially in impulsivity, indicate the need for further research to tailor interventions precisely.
Publisher
Springer Science and Business Media LLC
Reference73 articles.
1. Alavi, S. S., Ferdosi, M., Jannatifard, F., Eslami, M., Alaghemandan, H., & Setare, M. (2012). Behavioral addiction versus substance addiction: Correspondence of psychiatric and psychological views. International Journal of Preventive Medicine, 3(4), 290.
2. Albein-Urios, N., Martinez-González, J. M., Lozano, Ó, Clark, L., & Verdejo-García, A. (2012). Comparison of impulsivity and working memory in cocaine addiction and pathological gambling: Implications for cocaine-induced neurotoxicity. Drug and Alcohol Dependence, 126(1–2), 1–6.
3. Alexander, G. E., DeLong, M. R., & Strick, P. L. (1986). Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annual Review of Neuroscience, 9(1), 357–381.
4. Balodis, I. M., & Potenza, M. N. (2020). Common neurobiological and psychological underpinnings of gambling and substance-use disorders. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 99, 109847.
5. Barbas, H., & Pandya, D. N. (1987). Architecture and frontal cortical connections of the premotor cortex (area 6) in the rhesus monkey. The Journal of Comparative Neurology, 256, 211–288.
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