Assessment of deoxyhypusine hydroxylase as a putative, novel drug target
Author:
Publisher
Springer Science and Business Media LLC
Subject
Organic Chemistry,Clinical Biochemistry,Biochemistry
Link
http://link.springer.com/content/pdf/10.1007/s00726-009-0406-9.pdf
Reference32 articles.
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2. Abbruzzese A, Park MH, Folk JE (1985) Deoxyhypusine hydroxylase from rat testis. J Biol Chem 261:3085–3089
3. Andrus L, Szabo P, Grady RW, Hanauske RW, Hanauske AR, Huima-Byron T, Slowinska B, Zagulska S, Hanauske-Abel HM (1998) Antiretroviral effects of deoxyhypusine hydroxylase inhibitors: a hypusine-dependent host cell mechanism for replication of human immunodeficiency virus type 1 (HIV-1). Biochem Pharmacol 55:1807–1818
4. Beninati S, Abbruzzese A, Folk JE (1990) High-performance liquid chromatographic method for determination of hypusine and deoxyhypusine. Anal Biochem 184:16–20
5. Clement HM, Hanauske-Abel HM, Wolff EC, Kleinman HK, Park MH (2003) The antifungal drug ciclopirox inhibits deoxyhypusine and proline hydroxylation, endothelial cell growth and angiogenesis in vitro. Int J Cancer 106:458–459
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