Neuroprotective effect of newly synthesized 4-aminopyridine derivatives on cuprizone-induced demyelination in mice—a behavioral and immunohistochemical study
Author:
Funder
Medical University of Sofia, Bulgaria
Publisher
Springer Science and Business Media LLC
Subject
Organic Chemistry,Clinical Biochemistry,Biochemistry
Link
https://link.springer.com/content/pdf/10.1007/s00726-021-03035-2.pdf
Reference35 articles.
1. Acs P, Selak MA, Komoly S, Kalman B (2013) Distribution of oligodendrocyte loss and mitochondrial toxicity in the cuprizone-induced experimental demyelination model. J Neuroimmunol 262:128–131. https://doi.org/10.1016/j.jneuroim.2013.06.012
2. Asano M, Wakabayashi T, Ishikawa K, Kishimoto H (1978) Mechanism of the formation of megamitochondria by copper-chelating agents. IV. Role of fusion phenomenon in the cuprizone-induced megamitochondrial formation. Acta Pathol Jpn 28:205–213. https://doi.org/10.1111/j.1440-1827.1978.tb00532.x
3. Bacia A, Wollmann R, Soliven B (2004) K+ channel blockade impairs remyelination in the cuprizone model. Glia 48:156–165. https://doi.org/10.1002/glia.20067
4. Bakker DA, Ludwin SK (1987) Blood-brain barrier permeability during cuprizone-induced demyelination. Implications for the pathogenesis of immune-mediated demyelinating diseases. J Neurol Sci 78:125–137. https://doi.org/10.1016/0022-510X(87)90055-4
5. Biancotti JC, Kumar S, de Vellis J (2008) Activation of inflammatory response by a combination of growth factors in cuprizone-induced demyelinated brain leads to myelin repair. Neurochem Res 33:2615–2628. https://doi.org/10.1007/s11064-008-9792-8
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