Structure determination needs to go viral-Reference-Cited by-同舟云学术

Structure determination needs to go viral

Published:2024-01-29 Issue:1 Volume:56 Page:
ISSN:1438-2199
Container-title:Amino Acids
language:en
Short-container-title:Amino Acids

Author:

de Bastos Balbe e Gutierres Matheus^ORCID,Pedebos Conrado^ORCID,Bacaicoa-Caruso Paula^ORCID,Ligabue-Braun Rodrigo^ORCID

Abstract

AbstractViral diseases are expected to cause new epidemics in the future, therefore, it is essential to assess how viral diversity is represented in terms of deposited protein structures. Here, data were collected from the Protein Data Bank to screen the available structures of viruses of interest to WHO. Excluding SARS-CoV-2 and HIV-1, less than 50 structures were found per year, indicating a lack of diversity. Efforts to determine viral structures are needed to increase preparedness for future public health challenges.

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Publisher

Springer Science and Business Media LLC

Subject

Organic Chemistry,Clinical Biochemistry,Biochemistry

Link

https://link.springer.com/content/pdf/10.1007/s00726-023-03374-2.pdf

Reference21 articles.

1. Batool M, Ahmad B, Choi S (2019) A structure-based drug discovery paradigm. Int J Mol Sci 20:2783. https://doi.org/10.3390/ijms20112783

2. Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE (2000) The protein data bank. Nucleic Acids Res 28:235–242. https://doi.org/10.1093/nar/28.1.235

3. Burley SK, Bhikadiya C, Bi C, Bittrich S, Chen L, Crichlow GV, Christie CH, Dalenberg K, Di Costanzo L, Duarte JM, Dutta S, Feng Z, Ganesan S, Goodsell DS, Ghosh S, Green RK, Guranović V, Guzenko D, Hudson BP, Lawson CL, Liang Y, Lowe R, Namkoong H, Peisach E, Persikova I, Randle C, Rose A, Rose Y, Sali A, Segura J, Sekharan M, Shao C, Tao YP, Voigt M, Westbrook JD, Young JY, Zardecki C, Zhuravleva M (2021) RCSB protein data bank: powerful new tools for exploring 3D structures of biological macromolecules for basic and applied research and education in fundamental biology, biomedicine, biotechnology, bioengineering and energy sciences. Nucleic Acids Res 49:D437–D451. https://doi.org/10.1093/nar/gkaa1038

4. Carlson CJ, Albery GF, Merow C, Trisos CH, Zipfel CM, Eskew EA, Olival KJ, Ross N, Bansal S (2022) Climate change increases cross-species viral transmission risk. Nature 607:555–562. https://doi.org/10.1038/s41586-022-04788-w

5. Chatterjee P, Nair P, Chersich M, Terefe Y, Chauhan AS, Quesada F, Simpson G (2021) One health, “Disease X” & the challenge of “Unknown” unknowns. Indian J Med Res 153:264–271. https://doi.org/10.4103/ijmr.IJMR_601_21