PYCR, a key enzyme in proline metabolism, functions in tumorigenesis
Author:
Funder
National Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC
Subject
Organic Chemistry,Clinical Biochemistry,Biochemistry
Link
https://link.springer.com/content/pdf/10.1007/s00726-021-03047-y.pdf
Reference70 articles.
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2. Burke L, Guterman I, Palacios Gallego R, Britton RG, Burschowsky D, Tufarelli C, Rufini A (2020) The Janus-like role of proline metabolism in cancer. Cell Death Discov 6:104. https://doi.org/10.1038/s41420-020-00341-8
3. Cai F, Miao Y, Liu C, Wu T, Shen S, Su X, Shi Y (2018) Pyrroline-5-carboxylate reductase 1 promotes proliferation and inhibits apoptosis in non-small cell lung cancer. Oncol Lett 15(1):731–740. https://doi.org/10.3892/ol.2017.7400
4. Chen S, Yang X, Yu M, Wang Z, Liu B, Liu M, Liu L, Ren M, Qi H, Zou J, Vucenik I, Zhu WG, Luo J (2019a) SIRT3 regulates cancer cell proliferation through deacetylation of PYCR1 in proline metabolism. Neoplasia 21(7):665–675. https://doi.org/10.1016/j.neo.2019.04.008
5. Chen XY, Zhang J, Zhu JS (2019b) The role of m(6)A RNA methylation in human cancer. Mol Cancer 18(1):103. https://doi.org/10.1186/s12943-019-1033-z
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