A conformationally restricted GABA analogue based on octahydro-1H-cyclopenta[b]pyridine scaffold-Reference-Cited by-同舟云学术

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A conformationally restricted GABA analogue based on octahydro-1H-cyclopenta[b]pyridine scaffold

Published:2018-10-04 Issue:2 Volume:51 Page:255-261
ISSN:0939-4451
Container-title:Amino Acids
language:en
Short-container-title:Amino Acids

Author:

Melnykov Kostiantyn P.,Volochnyuk Dmitriy M.,Ryabukhin Sergey V.,Rusanov Eduard B.,Grygorenko Oleksandr O.

Funder

Enamine Ltd

Publisher

Springer Science and Business Media LLC

Subject

Organic Chemistry,Clinical Biochemistry,Biochemistry

Link

http://link.springer.com/article/10.1007/s00726-018-2660-1/fulltext.html

Reference32 articles.

1. Aceña JL, Sorochinsky AE, Soloshonok V (2014) Asymmetric synthesis of α-amino acids via homologation of Ni(II) complexes of glycine Schiff bases. Part 3: Michael addition reactions and miscellaneous transformations. Amino Acids 46:2047–2073. https://doi.org/10.1007/s00726-014-1764-5

2. Bordwell FG (1988) Equilibrium acidities in dimethyl sulfoxide solution. Acc Chem Res 21:456–463. https://doi.org/10.1021/ar00156a004

3. Cativiela C, Ordóñez M (2009) Recent progress on the stereoselective synthesis of cyclic quaternary alpha-amino acids. Tetrahedron Asymmetry 20:1–63. https://doi.org/10.1016/j.tetasy.2009.01.002

4. Chebib M, Allan RD, Duke RK, Johnston GAR (2001) The effects of cyclopentane and cyclopentene analogues of GABA at recombinant GABAC receptors. Eur J Pharmacol 430:185–192. https://doi.org/10.1016/S0014-2999(01)01390-5

5. Crittenden DL, Jordan MJT, Chebib M, Crittenden DL, Park A, Qiu J, Silverman RB, Duke RK, Johnston GAR (2006) Enantiomers of cis-constrained and flexible 2-substituted GABA analogues exert opposite effects at recombinant GABA(C) receptors. Bioorg Med Chem 14:447–455. https://doi.org/10.1016/j.bmc.2005.08.037

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