The competitive NMDA antagonist CPP protects substantia nigra neurons from MPTP-induced degeneration in primates-Reference-Cited by-同舟云学术

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The competitive NMDA antagonist CPP protects substantia nigra neurons from MPTP-induced degeneration in primates

Published:1993-12 Issue:6 Volume:348 Page:586-592
ISSN:0028-1298
Container-title:Naunyn-Schmiedeberg's Archives of Pharmacology
language:en
Short-container-title:Naunyn-Schmiedeberg's Arch Pharmacol

Author:

Lange Klaus W.,L�schmann Peter-Andreas,Sofic Emin,Burg Matthias,Horowski Reinhard,Kalveram Karl T.,Wachtel Helmut,Riederer Peter

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology,General Medicine

Link

http://link.springer.com/article/10.1007/BF00167234/fulltext.html

Reference36 articles.

1. Bormann J (1989) Memantine is a potent blocker of N-methyl-d-aspartat (NMDA) receptor channels. Eur J Pharmacol 166:591?592

2. Burns RS, Chiueh CC, Markey SP, Ebert MH, Jacobowitz DM, Kopin IJ (1983) A primate model of parkinsonism; selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Proc Natl Acad Sci USA 80:4546?4550

3. Carboni S, Melis F, Pani L, Hadliconstantinou M, Rossetti Z (1990) The non-competitive NMDA-receptor antagonist MK-801 prevents the massive release of glutamate and aspartate from rat striatum induced by 1-methyl-4-phenylpyridinium (MPP+). Neurosci Lett 117:129?133

4. Castagnoli A Jr, Chiba K, Trevor AJ (1985) Potential bioactivation pathways for the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Life Sci 36:225?230

5. D'Amato RJ, Alexander GM, Schwartzman RJ, Kitt AC, Price DL, Snyder SH (1987) Neuromelanin: a role in MPTP-induced neurotoxicity. Life Sci 40:705?712

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