Early administration of propofol protects against endotoxin-induced acute lung injury in rats by inhibiting the TGF-β1-Smad2 dependent pathway
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology,Immunology
Link
http://link.springer.com/content/pdf/10.1007/s00011-009-0110-y.pdf
Reference28 articles.
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3. Wesselkamper SC, Case LM, Henning LN, Borchers MT, Tichelaar JW, Mason JM, et al. Gene expression changes during the development of acute lung injury: role of transforming growth factor-β. Am J Respir Crit Care Med. 2005;172:1399–411.
4. Fahy RJ, Lichtenberger F, McKeegan CB, Nuovo GJ, Marsh CB, Wewers MD. The acute respiratory distress syndrome: a role for transforming growth factor-ß1. Am J Respir Cell Mol Biol. 2003;28:499–503.
5. Kolb M, Margetts PJ, Anthony DC, Pitossi F, Gauldie J. Transient expression of IL-1ß induces acute lung injury and chronic repair leading to pulmonary fibrosis. J Clin Invest. 2001;107:1529–36.
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