Association of hyperhomocysteinemia with genetic variants in key enzymes of homocysteine metabolism and methotrexate toxicity in rheumatoid arthritis patients

Author:

Chaabane Souhir,Messedi Meriam,Akrout Rim,Ben Hamad Mariem,Turki Mouna,Marzouk Sameh,Keskes Leila,Bahloul Zouheir,Rebai Ahmed,Ayedi Fatma,Maalej Abdellatif

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology,Immunology

Reference43 articles.

1. Imboden JB, Hellmann DB, Stone JH. Rheumatoid Arthritis: the disease diagnosis and clinical features. Current rheumatology diagnosis and treatment. NY: McGraw Hill; 2006. pp. 161–9.

2. Carmona L, Cross M, Williams B, Lassere M, March L. Rheumatoid arthritis. Best Pract Res Clin Rheumatol. 2010. https://doi.org/10.1016/j.berh.2010.10.001 .

3. Whittle SL, Hughes RA. Folate supplementation and methotrexate treatment in rheumatoid arthritis: a review. Rheumatology. 2004;43:267–71

4. Hernanz A, Plaza A, Martin-Mola E, De Miguel E. Increased plasma levels of homocysteine and other thiol compounds in rheumatoid arthritis women. Clin Biochem. 1999;32:65–70.

5. Wållberg-Jonsson S, Cvetkovic JT, Sundqvist KG, Lefvert AK, Rantapää-Dahlqvist S. Activation of the immune system and inflammatory activity in relation to markers of atherothrombotic disease and atherosclerosis in rheumatoid arthritis. J Rheumatol. 2002;29:875–82.

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